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Burn skin lesions in mice and BPC 157 therapy effect. The effects of... | Download Scientific Diagram

Numerous inflammatory mediators, including tumor necrosis factor-alpha (TNF-α), interleukins (IL-1β, IL-6, IL-18), matrix metalloproteinases (MMPs), chemokine ligand 2 (CCL-2), monocyte chemoattractant protein-1 (MCP-1), nuclear factor kappa B (Nf-κB), transforming growth factor-beta (TGF-β), E-selectin, various adhesion molecules (ICAM-1, VCAM-1), toll-like receptors (TLRs), adiponectin, endothelial cell-selective adhesion molecule (ESAM), and interferon-gamma (INF-γ), are strongly implicated in diverse forms of diabetic complications [33], [34], [35]

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This type of nerve damage affects the hands and feet, causing them to feel as if they are wearing gloves or stockings, even though they are not