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Interestingly, in a 3-week non-alcoholic steatohepatitis mouse model, Elafibranor showed strong benefits on NASH with improvement in hepatic inflammation, necroptosis, and apoptosis, but did not alter pyroptosis [172]
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Level 2+ Well-conducted case control or cohort studies with a low risk of confounding or bias and a moderate probability that the relationship is causal
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