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Taking one recent example of how this could be relevant, a provocative study appeared recently that investigated the impact of 30% calorie restriction, as well 68% amino acid and 68% BCAA reduction on ovarian reserve in young female C57BL/6 mice, the same strain used in many of the previously described mouse studies (Veiga et al., 2024)

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With aging being a major risk factor for mortality and morbidity in influenza infection, we assessed if these changes in glutathione metabolism after infection are different in aged versus young mice